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產(chǎn)品中心抗體Polyclonal AntibodyK106504PAnti-Delta4 Polyclonal Antibody
產(chǎn)品型號：K106504P
更新時間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
訪 問 量 ：1068
010-50973130
產(chǎn)品分類
Anti-Delta4 Polyclonal Antibody
| 英文名稱 | Anti-Delta4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | DLL4;AOS6;DLL 4;hdelta2;MGC126344 |
| 應(yīng)用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 75kDa |
| Gene ID | 54567 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human Delta4 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human Delta4 |
| Subcellular Locations | Cell membrane |
| Swiss Prot | Q9NR61 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium. |
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